snoop and the cake caper by M. Elaine Marsea, Imero Gobbato

By M. Elaine Marsea, Imero Gobbato

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The absence of R&D and interest in manufacturing new drugs for the NTDs reflects their market failure. The last 50 years have been a dark age for the R&D and manufacture of NTDs drugs and vaccines. 4. New Promise Through Public Private Partnerships Are we emerging from the dark ages? , and later, GlaxoSmithKline and Pfizer, inaugurated a series of extraordinary NTDs drug donation programs. org) began after the announcement by Roy Vagelos, Merck CEO, that his company would donate the drug free of charge for as long as needed to anyone with river blindness (Levine, 2004a).

Trans R Soc Trop Med Hyg 78, 351–3. E. (1993). Acid-base status in paediatric Plasmodium falciparum malaria. Q J Med 86, 99–109. E. (2004). Differentiating the pathologies of cerebral malaria by postmortem parasite counts. Nat Med 10, 143–5. S. (2003). Illness in England, Wales, and Northern Ireland associated with foreign travel: a baseline report to 2002. Health Protection Agency, London. S. (1992). Prognostic risk factors and post mortem findings in cerebral malaria in children. Trans R Soc Trop Med Hyg 86, 491–3.

1. Blood Tests Once the diagnosis is made, repeat blood films for parasite counts may be useful in following the progress of the disease. However, the paediatrician should be aware that, as quinine acts upon the later stages (schizonts), which are the generally sequestered in the microcirculation and thus not generally visible to the microscopist examining the blood film (that generally examines the circulating younger ring stages), peripheral parasitemia might continue to increase over the first 24 hours.

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