By John B. West MD PhD
Read Online or Download Respiratory Physiology: The Essentials PDF
Best pulmonary & thoracic medicine books
Bronchial asthma: A Clinician's consultant comprises the recent nationwide middle Lung and Blood Institute's 2007 directions for the analysis and administration of bronchial asthma (EPR-3) and emphasizes the significance of bronchial asthma keep watch over that has come to the vanguard of bronchial asthma administration. This important textual content discusses the present information on genetics and techniques to beat therapy disparities.
Quinolones in Pulmonary Tuberculosis Management
This state of the art reference offers targeted details at the use of quinolone antibiotics and different antibiotic regimens within the administration of pulmonary tuberculosis-offering in-depth assurance of the background, epidemiology, scientific presentation, prognosis, immunopathology, and immunotherapy of tuberculosis for the nonspecialist.
This complete revision of the well-received first variation offers every thing clinician treating sufferers with cystic fibrosis will want in one quantity. a great deal of new info has accrued over the past 5 years, starting from advances within the easy clinical figuring out of the , via novel therapies to advancements within the supply of care either within the medical institution and the house.
Physical Medicine and Rehabilitation Patient-Centered Care: Mastering the Competencies
Equipped round the six center abilities for physicians training rehabilitation medication as required by means of the ACGME, actual medication and Rehabilitation Patient-Centered Care: studying the capabilities is a special, self-directed textual content for citizens. masking all features of patient-centered care within the perform of actual medication and rehabilitation, the booklet offers a competency-based method of subject matters and stipulations quite often encountered during this area of expertise.
- Fibrosis Research: Methods and Protocols (Methods in Molecular Medicine)
- Acute Respiratory Infections (Oxford Respiratory Medicine Library)
- Fibrosis Research: Methods and Protocols (Methods in Molecular Medicine)
- Pathology of Lung Disease: Morphology – Pathogenesis – Etiology
- Pathology of Lung Disease: Morphology – Pathogenesis – Etiology
Extra resources for Respiratory Physiology: The Essentials
Sample text
Diffusion through a tissue sheet. The amount of gas transferred is proportional to the area (A), a diffusion constant (D), and the difference in partial pressure (P1 − P2), and is inversely proportional to the thickness (T). The constant is proportional to the gas solubility (Sol) but inversely proportional to the square root of its molecular weight (MW). indd d 25 25 6/18/2011 6/18/ 8/2 /2011 9:49:16 9:49:16 AM 26 Chapter 3 Fick’s Law of Diffusion • The rate of diffusion of a gas through a tissue slice is proportional to the area but inversely proportional to the thickness • Diffusion rate is proportional to the partial pressure difference • Diffusion rate is proportional to the solubility of the gas in the tissue but inversely proportional to the square root of the molecular weight ▲ Diffusion and Perfusion Limitations Suppose a red blood cell enters a pulmonary capillary of an alveolus that contains a foreign gas such as carbon monoxide or nitrous oxide.
In addition, the rate of transfer is proportional to a diffusion constant, which depends on the properties of the tissue and the particular gas. The constant is proportional to the solubility of the gas and inversely proportional to the square root of the molecular weight (Figure 3-1). This means that CO2 diffuses about 20 times more rapidly than does O2 through tissue sheets because it has a much higher solubility but not a very different molecular weight. O2 P2 Are a CO2 Vgas ∝ A . D . (P1 – P2) T D∝ Sol MW P1 Thickness Figure 3-1.
Q UEST I O N S For each question, choose the one best answer. 1. Using Fick’s law of diffusion of gases through a tissue slice, if gas X is 4 times as soluble and 4 times as dense as gas Y, what is the ratio of the diffusion rates of X to Y? A. B. C. D. E. 5 2 4 8 2. An exercising subject breathes a low concentration of CO in a steady state. 5 mm Hg and the CO uptake is 30 ml·min−1, what is the diffusing capacity of the lung for CO in ml·min−1·mm·Hg−1? A. B. C. D. E. 20 30 40 50 60 3. In a normal person, doubling the diffusing capacity of the lung would be expected to A.