Laboratory animal anaesthesia: a practical introduction for by P A Flecknell

By P A Flecknell

Using secure and potent anaesthetic suggestions could have an incredible impression either at the welfare of laboratory animals and the standard of the study effects acquired in utilizing them. In occasions of justified public and clinical matters over such matters, the necessity for transparent and concise suggest on sturdy procedure is of paramount significance. besides the fact that, a lot anaesthetic paintings within the laboratory is conducted through research Read more...

Show description

Read or Download Laboratory animal anaesthesia: a practical introduction for research workers and technicians PDF

Best introduction books

Student Solutions Manual - Introduction to Programming Using Visual Basic 2010

An creation to Programming utilizing visible uncomplicated 2010, 8th version, — regularly praised by means of either scholars and teachers — is designed for college students without past laptop programming event. Now up to date for visible simple 2010, Schneider specializes in educating problem-solving talents and sustainable programming abilities.

Many-Body Problems and Quantum Field Theory: An Introduction

"Many-Body difficulties and Quantum box idea" introduces the techniques and strategies of the themes on a degree appropriate for graduate scholars and researchers. The formalism is built in shut conjunction with the outline of a couple of actual structures: solidarity and dielectric homes of the electron fuel, superconductivity, superfluidity, nuclear subject and nucleon pairing, subject and radiation, interplay of fields via particle alternate and mass new release.

Additional resources for Laboratory animal anaesthesia: a practical introduction for research workers and technicians

Example text

It is possible to intubate lightly anaesthetized animals but, whilst this may be desirable under some circumstances, it is advisable to gain some proficiency in the technique of intubation before attempting this. /. Dogy cat and sheep. The animal is placed in sternal recumbency and its jaws opened as widely as possible by an assistant. The tongue is drawn forwards and the laryngoscope advanced over the tongue towards the pharynx. The larynx is usually masked by the epiglottis. Gentle upwards pressure on the soft palate with the end of the endotracheal tube will disengage the epiglottis, allowing it to fall forwards, so providing an unobstructed view of the larynx.

6-9 ml kg~^ min"^ for a 3 kg animal) (Brody, 1945), but for practical reasons it is more usual to operate the circle system as a low-flow rather than completely closed circuit. Typically, fresh gas flows of 100 ml kg~ ^ min~^ are used for small animals (< 10 kg) and 20-30 ml kg~^ min ~^ for larger animals. This represents a major advantage of circle systems in comparison with other circuits in controlling anaesthetic costs. The newer anaesthetic agents such as isoflurane are expensive, and in larger animals the use of a closed system, where appropriate, can reduce costs (Appendix 2).

Sevoflurane and desflurane. Sevoflurane and desflurane are potent anaesthetic agents with characteristics similar to isoflurane. Desflurane (I653) has been released for clinical use in humans, but requires a newly designed pressurized vaporizer to provide stable concentrations of the anaesthetic. It undergoes the least degree of metabolism (Koblin, 1992) and induction and recovery from anaesthesia are the most rapid of the volatile anaesthetics (Eger, 1992). Sevoflurane undergoes a similar degree of metabolism as isoflurane, and is unstable in the presence of soda lime, the carbon dioxide absorber used most commonly in closed circuit anaesthesia.

Download PDF sample

Rated 4.18 of 5 – based on 29 votes