By PD. Dr. Clemens Fritsch, Univ.-Prof. Dr. Dr. h.c. Thomas Ruzicka (auth.)
This booklet is the main up to date ebook on fluorescence diagnostic (FDAP) and photodynamic treatment (PDT) tools utilized in dermatology. either concepts are shortly all over the world brought as criteria for the delineation and the remedy of cutaneous precancerous phases and tumors, which convey progressively expanding numbers because of e.g. extra common solar publicity. Summarizing studies on greater than 5.000 handled sufferers, it bargains a entire details on each point of pores and skin tumor detection and therapy. the most a part of the e-book makes a speciality of the scientific facets giving designated descriptions on pores and skin tumor detection in addition to photodynamic therapy of chosen illnesses (solar keratoses, basal phone carcinomas, squamous phone carcinomas, Bowen's disorder, psoriasis lesions, etc.). The clinically orientated chapters are supplemented via functional instructions for PDT and FDAP. The incorporated atlas is constructed from 270 top of the range colour figures permitting day-by-day use as a handbook.
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Additional info for Fluorescence Diagnosis and Photodynamic Therapy of Skin Diseases: Atlas and Handbook
62). After treatment with salicylic acid (5%) ointment, fluorescence is more homogeneous (Fig. 64) To achieve best results in FDAP, it is recommendable to remove any hyperkeratotic crusts (Figs. 61-64). The medium strong fluorescence in lesions of lupus erythematosus and in patches of mycosis fungoides supports the idea that these diseases could be approachable to PDT. Even cutaneous B-cell lymphoma displayed high fluorescence in FDAP (Figs. 65 and 66). There may be several reasons for the slight fluorescence intensity in malignant melanomas.
In the case of the facial Becs the lesions showed partly a weaker definition (range: 92-94% of the total lesion areas) (Table 6). Fluorescence intensity. 9-3). v In VII'O Results Fluorescence intensities of treated tissues. In SK, fluorescence intensity was higher using topical treatment with ALA than ALA-ME for 6 h. In normal skin, fluorescence was weaker for ALA-ME than for ALA (Table 3). Table 3. 2 Fluorescence intensities of skin treated by ALA or ALA methylester irradiated by Wood's light (370-410 nm, 10 cm distance, S mW/cm'). Values are given semiquantitatively according to a fluorescence standard: 0 = no fluorescence, 3 = maximum fluorescence (n = 8; mean ± SEM).
In VII'O Results Fluorescence intensities of treated tissues. In SK, fluorescence intensity was higher using topical treatment with ALA than ALA-ME for 6 h. In normal skin, fluorescence was weaker for ALA-ME than for ALA (Table 3). Table 3. 2 Fluorescence intensities of skin treated by ALA or ALA methylester irradiated by Wood's light (370-410 nm, 10 cm distance, S mW/cm'). Values are given semiquantitatively according to a fluorescence standard: 0 = no fluorescence, 3 = maximum fluorescence (n = 8; mean ± SEM).