Aspergillosis: from diagnosis to prevention by David W. Denning (auth.), Alessandro Comarú Pasqualotto

By David W. Denning (auth.), Alessandro Comarú Pasqualotto (eds.)

Aspergillosis is infection or allergic reaction brought on by the fungus Aspergillus. Aspergillus conidia are largely dispersed within the setting and will simply achieve human lungs and/or paranasal sinuses: most folks inhale Aspergillosis spores each day!

The label Aspergillosis is used for a number of diversified scientific stipulations. for example, invasive Aspergillosis usually impacts significantly immunocompromised sufferers similar to people with lengthy neutropenia or receiving treatment with steroids. nonetheless, allergic varieties of Aspergillosis reason exuberant scientific syndromes that generally have an effect on sufferers with bronchial asthma and cystic fibrosis. Slowly harmful lung ailments can also take place within the it sounds as if immunocompentent host, in particular within the context of earlier harm to the lung structure. those are difficult-to-diagnose infections, and diagnostic checks practice another way looking on the categorical scenario.

This publication summarizes the present wisdom approximately Aspergillosis, covering:

  • Epidemiology
  • Pathogenesis
  • Clinical manifestations
  • Diagnosis
  • Treatment
  • Prevention

Written by way of across the world revered authors, the data awarded during this booklet provides for a greater figuring out of Aspergillosis by way of offering a finished and transparent evaluation of all features linked to this advanced disease.

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Mol Immunol, 45, 1485–1493. 33. , Maloukou, A. & Roilides, E. (2003) Antifungal activity of human polymorphonuclear and mononuclear phagocytes against non-fumigatus Aspergillus species. Mycoses, 46, 77–83. Differences and Similarities Amongst Pathogenic Aspergillus Species 29 34. Blanco, J. , Caballero, J. & Garcia, M. E. (1998) Aspergillosis: Mechanisms of pathogenicity implicated and approach to laboratory diagnosis. Rev Iberoam Micol, 15, 10–15. 35. Latge, J. P. (1999) Aspergillus fumigatus and aspergillosis.

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Balajee, S. , Gribskov, J. , Nickle, D. & Marr, K. A. (2005) Aspergillus lentulus sp. , a new sibling species of A. fumigatus. Eukaryot Cell, 4, 625–632. 70. Balajee, S. , Fothergill, A. & Marr, K. A. (2005) Mistaken identity: Neosartorya pseudofischeri and its anamorph masquerading as Aspergillus fumigatus. J Clin Microbiol, 43, 5996–5999. 71. Balajee, S. , Varga, J. & Marr, K. A. (2006) Molecular studies reveal frequent misidentification of Aspergillus fumigatus by morphotyping. Eukaryot Cell, 5, 1705–1712.

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