Advances in Biochemical Engineering, Volume 002 by T.K. Ghose ,A. Fiechter, N.Blakebrough

By T.K. Ghose ,A. Fiechter, N.Blakebrough

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B) On-line Processes . . . . . . . . . . . 5. Data-Analysis-Oriented Use of the Computer . . . . . a) Layout of Facilities . . . . . . . . . . . b) Computer and Software Capabilities . . . . . . . c) Computer Program . . . . . . . . . . . d) Functional Considerations . . . . . . . . . e) Validity Test of Experimental Results . . . . . . . 6. Process Control Oriented Use of Computers . . . . . a) Evaluation of the Use of DDC in Fermentation Processes .......

The third enzyme converted lactose to glucose and galactose, thus providing the reactant for the rest of the sequence. Again the overall rate was higher for the bound than soluble system. Goldman and Katehalski (1971) presented a theoretical analysis for two enzymes bound to the surface of an impermeable support. The reaction sequence was as follows: The authors assumed first-order kinetics with no products present initially in the bulk of the solution. They concluded that the presence of unstirred layers kept product P1 in the vicinity of the support surface so that reaction 2 proceeded more rapidly than if both enzymes were free in solution.

Conf. Struct. React. DFP Sensitive Enzymes, Stockholm 1966; Heilbron, E. ): pp. 59--68; Forskningsanstalt, Stockholm, Sweden 1967. Shrier, A. L. : In: Wingard, L. , Enzyme Engineering, pp. 323--326. New York: John Wiley 1972. : Biotech. Bioeng. 13, 309 (1971). : Bull. Math. Biophys. 33, 97 (1971). Sober, H. , Hartley, R. , Caroll, W. , Peterson, E. : In: Neurath, H. ): The Proteins, Vol. , pp. 2--98. New York: Academic Press 1964. J. :J. Theoret. Biol. 27, 221 (1970). S tesina, L. , Akopyan, Zh.

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